Urban Informatics for Sustainability and Resilience Center (UrbInSuRe) center will develop a cyber infrastructure platform for computational modeling and research data for interdisciplinary researchers and students. Some example science domains include agriculture, geography, hydrology, urban planning, environmental engineering, etc. The cyber infrastructure architecture has three major components: 1) scientific workflow system, 2) semantic data management system, 3) visualization. Using these components, applications for different use cases (or different science) can be built. The platform will support a collaborative process for seamlessly linking and sharing data acquisition and analysis, models, and workflows (sequences of analytical and modeling steps). These tools will be accessible through user-friendly, yet computationally powerful, Web applications for knowledge creation and decision support. This framework will support adaptive research and decision making to rapidly identify and advance new data and technology needs. The platform will be made available to campus and external users for open research, education, and engagement; users will be invited to contribute to advancing its capabilities through an open-source community.